Mayo Clinic expert highlights risk from serrated polyps
NEWS - 27TH OCTOBER 2021
New research indicates that people with hard-to-see serrated polyps should be checked more frequently for bowel cancer, explains Dr James East of Mayo Clinic Healthcare
Physicians screening people for bowel cancer are becoming increasingly concerned about a type of polyp once thought harmless: serrated polyps, sawtooth-edged growths in the colon that are flat, nearly translucent and sometimes difficult to spot during colonoscopies. New research suggests people with serrated polyps should be checked more frequently for bowel cancer, a Mayo Clinic Healthcare expert writes in a commentary in the journal Gut.
Bowel cancer, also known as colorectal cancer, begins at the end of the digestive tract, in the colon, and usually starts with small polyps that when benign cause no symptoms but gradually become cancerous. Colorectal cancer screening is aimed at detecting and removing polyps before they turn into cancer. There are different kinds of polyps, and until the relatively recent past, physicians were unconcerned about serrated polyps.
“Our view of serrated polyps has come a long way in the last two decades, moving from seeing them as benign lesions that do not develop into cancer, to recognising them as lesions that may account for up to one third of all colorectal cancers,” Dr James East, a gastroenterologist at Mayo Clinic Healthcare in the Harley Street Medical Area, notes in the commentary.
Frequent colonoscopies
Data to indicate whether people with serrated polyps need closer watching for colorectal cancer have been lacking, but a large new study by Dr Dan Li and colleagues at Kaiser Permanente published in Gut now suggests that people with serrated polyps alone or with another type of polyp called adenomas may need more frequent colonoscopies, Dr East says.
Adenomas have long been viewed as precursors to cancer; the Kaiser Permanente study shows that serrated polyps increase cancer risk by about the same amount as adenomas, and that the presence of both types of polyps raises risk still further, Dr East notes.
More research is needed to refine the estimation of cancer risk in people with serrated polyps alone or with adenomas and determine the best approach to screening for each patient, Dr East says.
One possibility would be moving away from measuring risk according to the type of polyp and instead focus on such markers as the number of polyps in combination with other bowel cancer risk factors such as obesity, a high-fat diet, smoking, heavy alcohol use or inflammatory intestinal diseases such as Crohn’s disease and ulcerative colitis, he adds.
-
NEWS
Schoen Clinic London awarded certification for patient safety
HSMA spinal and orthopaedic hospital named as a National Joint Registry (NJR) Quality Data Provider after completing detailed programme of audits
-
Q&A
Breast Cancer Awareness Month: prevention and treatment
Miss Jennifer Rusby, consultant oncoplastic breast surgeon at The Royal Marsden Private Care, on breast cancer prevention and improving cosmetic outcomes
-
NEWS
Breast Cancer Awareness Month: The Bra Sisters at The London Clinic
The Bra Sisters, run by two former breast cancer patients, launch a pop-up post-mastectomy bra fitting service at The London Clinic
-
NEWS
HSMA eye clinic demonstrates pioneering surgical techniques
The London Ophthalmology Centre set to demonstrate new less-invasive surgeries for glaucoma and lens replacement at Future Surgery 2021